RECENT PUBLICATIONS Z.
Gao, H.D. Fain, Z.
Gao, H.D. Fain, N.Y. Rapoport, D.A. Christensen, H. D. Fein, L. Barrows, Z. Gao (2004) Ultrasound-triggered drug targeting to tumors in vitro and in vivo. Ultrasonics 42: 943-950. Rapoport,
N. (2004) Factors Affecting Ultrasound Interactions with Polymeric Micelles and
Viable Cells. in: Carrier-Based Drug Delivery. ACS Symposium Series 879, S.
Swenson, Ed., Rapoport, N., Pitt, W.G., Sun Hao, Nelson, J.L. (2003) Drug Delivery in Polymeric Micelles: from in vitro to in vivo. J. Control Rel., 91: 85-95. Rapoport,
N. (2003) Controlled Drug Delivery to Drug-Sensitive and Multidrug Resistant
cells: Effects of Pluronic Micelles and Ultrasound. in: Advances in Controlled
Drug Delivery. ACS Symposium Book Series, ed. S. Dinh and P.
RELEVANT PUBLICATIONS (last three years).
Z. Gao, H.D. Fain, Micellar-Encapsulated
Drug and Ultrasound. Journal of Controlled Release 102 (1) 203-222. Z.
Gao, H.D. Fain, N.Y. Rapoport, D.A. Christensen, H. D. Fein, L. Barrows, Z. Gao (2004) Ultrasound-triggered drug targeting to tumors in vitro and in vivo. Ultrasonics, 42: 943-950. Patent US
6,649,702 Stabilization and Acoustic Activation of Polymeric Micelles for Drug
Delivery. Issued Rapoport, N. (2003) Controlled Drug Delivery to Drug-Sensitive and Multidrug Resistant cells: Effects of Pluronic Micelles and Ultrasound. in: Advances in Controlled Drug Delivery. ACS Symposium Series 846, S. Dinh and P. Liu, Eds., Washington, DC, 2003, pp. 85-101. Rapoport,
N. (2004) Factors Affecting Ultrasound Interactions with Polymeric Micelles and
Viable Cells. in: Carrier-Based Drug Delivery. ACS Symposium Series 879, S.
Swenson, Ed., Rapoport, N., Pitt, W.G., Sun Hao, Nelson, J.L. (2003) Drug Delivery in Polymeric Micelles: from in vitro to in vivo. J. Control Rel., 91: 85-95. Marin A, Sun Hao, Husseini GA, Pitt WG,
Christensen DA, Rapoport, N, Marin, A, Christensen, D.A. (2002) Ultrasound-Activated Drug Delivery. Drug Delivery Systems and Sciences, 2: 37-46. Rapoport,
N., Marin, A. Luo, Yi, Prestwich, G, Muniruzzaman, Md. (2002) Intracellular
Uptake and Trafficking of Pluronic Micelles in Drug-Sensitive and MDR Cells:
Effect on the Intracellular Drug Localization. J. Pharm. Sci. 91:
157-170. Husseini, G.A., Rapoport, N.Y., Christensen, D.A., Pruitt, J.D., Pitt, W.G. (2002) Kinetics of ultrasonic release of Doxorubicin from Pluronic P-105 micelles. Colloids and Surfaces B: Biointerfaces 24, 253-264. Marin, A., Muniruzzaman, M., Rapoport, N. (2001) Mechanism of the ultrasound activation of micellar drug delivery. J. Control. Rel. 75: 69-81 Marin,
A., Muniruzzaman, M., Rapoport, N. (2001) Acoustic activation of drug delivery
from polymeric micelles: effect of pulsed ultrasound. J. Control. Rel. 71:
239-249. Husseni,
G.A., Myrup, G.D., Pitt, W.G., Christensen, D.A., Rapoport,
N., Marin, A.P., Timoshin, A.A. (2000) Effect of a polymeric surfactant on
electron transport in HL-60 cells. Arch. Biochem. Biophys. 384:
100-108. Pruitt, J.D., Husseini, G., Rapoport, N., Pitt, W.G. (2000) Stabilization of Pluronic P-105 micelles with an interpenetrating network of N,N-diethylacrylamide. Macromolecules 33: 9306-9309. Rapoport,
N. Stabilization and acoustic activation of Pluronic micelles for tumor-targeted
drug delivery (1999) Colloids and Surface
B: Biointerfaces, 3: 93-111. Husseini, G., El-Fayoumi, R.,
O’Neil, K., Rapoport, N, Pitt, W. (1999) DNA damage induced by micellar-delivered
Doxorubicin and ultrasound: comet assay study. Cancer Letters 154:
211-216
Rapoport,
N., Pitt, W.G., Smirnov, A.I., and Timoshin, A.I.(1999)
Bioreduction of Tempone and Spin-labeled Gentamicin by P.
aeruginosa cells: Kinetics and Effect of Ultrasound. Archives Biochem. Biophys.,
362: 233-241 Selected project-related publications
(earlier years) Rapoport,
N., Munshi N., Pitina, L, Pitt W.G.
(1997) Pluronic micelles as vehicles for tumor-specific delivery of two
anticancer drugs to HL-60 cells using acoustic activation. Polymer
Preprints 38: 620-621 Rapoport,
N. and Pitina, L (1998) Intracellular distribution and intracellular dynamics of
a spin-labeled analog of Doxorubicin by fluorescence and EPR spectroscopy.
J. Pharm. Sci. 87:
321-325. Munshi,
N., Rapoport, N., Pitt, W.G. (1997) Ultrasonic activated drug delivery from
Pluronic P-105 micelles. Cancer Letters
117: 1-7 . Rapoport,
N., Smirnov, A., Timoshin, A., Pitt, W.G., Pratt, A.M. (1997) The effect of
ultrasound on the permeability of P.
aeruginosa cell membranes as probed by the uptake of lipophilic spin probe. Archives
of Biochemistry and Biophysics 344:114-124. Rapoport,
N., Caldwell, K. (1994) Structural transitions in micellar solutions of Pluronic
P-105: an electron paramagnetic resonance investigation. Colloids
and Surfaces B: Biointerfaces, 3: 217-228 Li,
J.-T., Rapoport,
N. and Tresco, P. A. (1994) Developing Paramagnetic Polymeric Membranes for
Tracking Transplanted Cells. in: Biomedical
Engineering Recent Developments. Ed.J. Vossoughi, University of
Books, book chapters, and reviews: Rapoport, N. Controlled Drug Delivery to Drug-Sensitive and Multidrug Resistant cells: Effects of Pluronic Micelles and Ultrasound. ACS Book Series, 2002, in print. N.
Rapoport and A.A. Efros (1995). Popov,
A.A., Rapoport, N. Ya and Zaikov, G.E., Oxidation
of Stressed Polymers, Gordon and Breach Science Publishers, 1991, 333 pp. White,
J.A. and Rapoport, N., Stress Effects on Polymer Durability in the Oxidative
Environment. A review. Trends in Polymer
Science 1994, 2: 197-202
BOOKS AND BOOK CHAPTERS: Rapoport,
N. (2004) Factors Affecting Ultrasound Interactions with Polymeric Micelles and
Viable Cells. in: Carrier-Based Drug Delivery. ACS Symposium Series 879, S.
Swenson, Ed., Rapoport,
N., Marin, SA., Popov,
A.A., Rapoport, N. Ya and Zaikov, G.E., Oxidation
of Stressed Polymers, Gordon and Breach Science Publishers, 1991, 333 pp. N.
Rapoport and A.A. Efros (1995). White, J.A. and Rapoport, N., Stress Effects on Polymer Durability in the Oxidative Environment. A review. Trends in Polymer Science 1994, 2: 197-202
PATENTS Rapoport,
N. Synergistic compositions for the prevention of polymer degradation. Rapoport, N, Pitt, W.G. Acoustically Activated Localized Drug Delivery.
Member of the American Chemical Society
Member of the Controlled Release Society Member of the International EPR Society
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